Great texture
A very moisturizing serum.
Needle-less® Growth Factor Serum
Needle-less® Growth Factor Serum
1 fl oz
The problem with most anti-aging serums is simple: they promise results but rarely prove they work. Many claim to smooth, firm, and lift—but where’s the evidence?
When we created Needle-less® Growth Factor Serum, we set out to do things differently. Instead of adding just another product to the lineup, we took a smarter approach—grounded in advanced technology and proven by real clinical testing.
In a 12-week, double-blind, IRB-approved clinical trial, Needle-less® Growth Factor Serum was tested head-to-head against SkinMedica’s TNS Advanced+ Serum, the industry’s best-known growth factor serum (sold at nearly 4x the price). The results spoke for themselves:
- Investigator-assessed improvements in skin texture and firmness were significantly higher for Needle-less® at both Week 8 and Week 12
- On the Global Aesthetic Improvement Scale (GAIS) at Week 12, Needle-less® Growth Factor Serum showed 30% greater overall improvement than the competitor
- It outperformed the leading growth factor serum in 73% of performance indicators
In other words, this isn’t just another serum with empty promises. It’s clinically proven skincare technology that reframes how we approach aging—helping skin look visibly lifted and visibly renewed.
Regular price
$69.00
Regular price
$69.00
Sale price
Unit price
per
Full Size
Mini
FREE GIFT
Get a Free SmrtSun SPF
with your full size Needle-less® Growth Factor Serum purchase.
$28 VALUE
BROAD SPECTRUM
AUTO-APPLIED
Needle-less® Growth Factor Serum
Visibly firm and lift skin with amino-acid biogrowth factors.
$69.00
Couldn't load pickup availability
-
Ordered
- - -
Order Ready
- - -
Delivered
Before
After
Before and After 12 Weeks Of Use
When using the Needle-less® Growth Factor Serum as directed. Unedited and not retouched. Results may vary.
Discover Next-Gen Skincare, Backed by Biotech
Discover Next-Gen Skincare, Backed by Biotech
90%
of participants showed visible improvement by week 12*
73%
of performance indicators showed DRMTLGY outperformed SkinMedica's $295 TNS Advanced+ Serum*
30%
greater visible improvement than SkinMedica's $295 TNS Advanced+ Serum*
*Based on a 12 week double-blind IRB-approved clinical trial of 20 participants.
4 Reasons You’ll Love Needle-less® Growth Factor Serum
001
Mimics the Skin's Natural Regenerative Signals
A blend of 5 bio-engineered growth factor peptides mimics your skin’s repair messengers, encouraging faster cell renewal without the use of human-derived ingredients.
002
Visibly Lifts & Firms
Clinically tested to deliver real results. 90% of participants noticed skin felt firmer, improved clarity & tone, and an improvement in overall appearance in just 12 weeks.*
003
Outperformed the Leading Growth Factor Serum at ¼ the price
In a 12-week IRB-approved, randomized, double-blinded, controlled clinical trial, our formula delivered 30% greater overall visible improvement, without the $295 price tag.
004
Repairs & Strengthens Skin Barrier
This serum features our CeraPep™ Technology, a proprietary blend of ceramides and peptides that restores the barrier’s essential lipids. So not only does this all-new formula lift and firm, but it’s proven to strengthen skin’s barrier after just one use.
Dr. Dayan on Needle-less® Growth Factor Serum:
“In this 12-week clinical study, participants were split into two groups—each applying a different topical treatment twice daily. Preliminary results showed visible improvements in wrinkles, texture, and firmness across both groups. One group used DRMTLGY's product, while the other used SkinMedica’s TNS Advanced+ Serum priced 4x more. However, the formula developed by DRMTLGY demonstrated notably superior results in skin texture and firmness.”
Dr. Dayan on Needle-less® Growth Factor Serum:
Dr. Steven H. Dayan
MD, FACSThe problem with most anti-aging serums is simple: they promise results but rarely prove they work. Many claim to smooth, firm, and lift—but where’s the evidence?
When we created Needle-less® Growth Factor Serum, we set out to do things differently. Instead of adding just another product to the lineup, we took a smarter approach—grounded in advanced technology and proven by real clinical testing.
In a 12-week, double-blind, IRB-approved clinical trial, Needle-less® Growth Factor Serum was tested head-to-head against SkinMedica’s TNS Advanced+ Serum, the industry’s best-known growth factor serum (sold at nearly 4x the price). The results spoke for themselves:
- Investigator-assessed improvements in skin texture and firmness were significantly higher for Needle-less® at both Week 8 and Week 12
- On the Global Aesthetic Improvement Scale (GAIS) at Week 12, Needle-less® Growth Factor Serum showed 30% greater overall improvement than the competitor
- It outperformed the leading growth factor serum in 73% of performance indicators
In other words, this isn’t just another serum with empty promises. It’s clinically proven skincare technology that reframes how we approach aging—helping skin look visibly lifted and visibly renewed.
Directions
Apply 1-2 pumps to clean skin in the morning or evening. Can be used daily or as directed by a physician.
Ingredients
Ingredient Highlights: Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Chiretta (Swertia Chirata) Extract, Mushroom (Tremella Fuciformis) Sporocarp Extract
All Ingredients: Water/Aqua/Eau, Glycerin, Butylene Glycol, Pentylene Glycol, Maltodextrin, Coco-Caprylate/Caprate, Saccharide Isomerate, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Triheptanoin, Chiretta (Swertia Chirata) Extract, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C9-12 Alkane, Polyurethane-100, Ethylhexylglycerin, Sodium Hydroxide, Lecithin, Trisodium Ethylenediamine Disuccinate, Acetyl Glutamine, 1,2-Hexanediol, Mushroom (Tremella Fuciformis) Sporocarp Extract, Hydrolyzed Hyaluronic Acid, Decyl Glucoside, Bacillus/Soybean Ferment Extract, Sodium Lauroyl Lactylate, Caprylyl Glycol, Carbomer, Polysorbate 20, Cholesterol, Xanthan Gum
DRMTLGY is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.
Skin Concerns
Wrinkles
Firmness
Texture
Dullness
Skin Types
- Normal
- Oily
- Dry
- Combination
How to Layer Needle-less® Growth Factor Serum
Complete Your Regimen
FacialRX™ Brightening Eye Masks
Awaken and revitalize tired eyes with biodegradable brightening masks.
Matte Universal Tinted Moisturizer SPF 46
This revolutionary hybrid sunscreen not only protects skin from harmful UV rays, but it...
20% OFFMakeup Minimalist Duo - Medium
Whether you prefer a more natural look or looking for a quick, easy routine...
SmrtSun Broad Spectrum SPF 45
This award-winning, lightweight SPF provides advanced broad-spectrum protection with skin-smoothing benefits. Knotweed Extract shields...
Neck Contouring Serum
Despite the skin on the neck being very delicate and prone to premature aging,...
20% OFFMakeup Minimalist Duo - Fair
Whether you prefer a more natural look or looking for a quick, easy routine...
Gentle Acne Cleanser
Why is it different? Our unique blend of Salicylic Acid, a powerful acne-fighting ingredient,...
What are people saying about Needle-less® Growth Factor Serum?
Customer Reviews
Based on verified customer reviews, the Needle-less® Growth Factor Serum helps reduce the appearance of fine lines and provides deep hydration. Reviewers note that their skin feels firmer and looks smoother with regular use.
This is an AI-generated summary of verified customer reviews.
LIKES
DISLIKES
No Trending Dislikes
Hydration
DryHydrated
Complexion
DullGlowy
Texture
RoughSmooth
Skin Comfort
SensitiveCalm
New favorite
I have used the similar products by TNS and Medik8 and I tried this after seeing the review by Dr Shah. I loved the TNS but way out of my budget and this seems to be keeping my skin pretty happy. Nice finish, not sticky. I use it under my vitamin c in the morning.
Quality Product
I really like this product. I am new at using it and look forward to the results.
well worth the cost
This is so much cheaper than TNS serum and seems to work well for me. It's hard to tell if it works as well but I have not noticed much difference since switching from TNS to this.
Great product
Love this product my skin has improved so much
Customer photos & videos
